The instrumental role of universities in socio-economic development is today widely recognised. Enhancing links and cross-fertilisation between Higher Education Institutions (HEIs) and their business environment in the interest of graduates’ employability, improved competitiveness and growth is high on the agenda of policy makers and HEIs around the globe. SMART project  proposes a set of focused and complementary activities for enhanced university-business cooperation at Indonesian HEIs to help them identify opportunities for development, generate research-based knowledge, and contribute to the on-going education in the field. The project will facilitate the transfer of good practices from the EU to the PC HEIs; the set-up of professional units (Business Engagement Centers) at 7 PC HEIs and training to their staff to let them accompany students and researchers in making their business ventures a reality. The creation of a University-Business Network, as a platform for dialogue and exchange of experiences, and the Start-Up Nights and other stakeholders’ events will also contribute to inspiring nation-wide change.